alexa Visceral adipose tissue is a better predictor of subclinical carotid atherosclerosis compared with waist circumference.


Internal Medicine: Open Access

Author(s): Rallidis LS, Baroutsi K, Zolindaki M, Karagianni M, Varounis C, , Rallidis LS, Baroutsi K, Zolindaki M, Karagianni M, Varounis C,

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Abstract We investigated whether visceral adipose tissue (VAT) measured by ultrasonography is better than waist circumference (WC) in predicting the presence of subclinical carotid atherosclerosis. We recruited 100 individuals without a history of cardiovascular disease or diabetes mellitus. VAT volume was measured by ultrasonography and common carotid artery intima-media thickness (CCA-IMT) by B-mode ultrasonography. Both VAT and WC were positively associated with body mass index, triglycerides, uric acid, systolic/diastolic blood pressure and high sensitivity C-reactive protein and inversely correlated with high-density lipoprotein cholesterol. However, only VAT was associated with CCA-IMT (r = 0.309, p = 0.002). Multivariate logistic regression analysis revealed that VAT, but not WC, was an independent predictor of carotid plaques after adjustment for cardiovascular risk factors (odds ratio [OR] = 1.017, 95\% confidence interval [CI] = 1.003-1.031, p = 0.017), and this association persisted after additional adjustment for WC (OR = 1.024, 95\% CI = 1.003-1.031, p = 0.027). Our data suggest that VAT volume measured by ultrasonography may be a better predictor of subclinical carotid atherosclerosis than waist circumference in healthy individuals. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved. This article was published in Ultrasound Med Biol and referenced in Internal Medicine: Open Access

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