Author(s): Kahloun R, Gargouri S, Abroug N, Sellami D, Ben Yahia S,
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Abstract Abstract Purpose: To characterize and analyze ocular involvement associated with visual loss in a cohort of patients with rickettsial disease. METHODS: Retrospective study of 16 eyes of 14 patients. RESULTS: Mean initial visual acuity (VA) was 20/63 (range, 20/800-20/25). White retinal lesions infiltrating inner retina was the most common finding occurring in 14 eyes (87.5\%). It was associated with a serous retinal detachment (SRD), accurately detectable by optical coherence tomography, in 11 eyes (78.6\%). Other findings included optic neuropathy in 7 eyes (43.75\%), cystoid macular edema in 1 eye (6.25\%), branch retinal artery occlusion in 1 eye (6.25\%), and choroidal neovascularization in 1 eye (6.25\%). Thirteen patients were treated with a 2-week course of oral doxycycline 200 mg/day. Mean final VA was 20/40. CONCLUSIONS: Inner retinitis, associated with mild vitritis and SRD, and optic neuropathy are the most common vision-threatening ocular manifestations of rickettsial disease.
This article was published in Ocul Immunol Inflamm
and referenced in Journal of Antivirals & Antiretrovirals