Author(s): Ribera Casado JM
Abstract Share this page
Abstract The aim of this review is to offer an updated survey about the relationship between old age, vitamin D and different clinical conditions. Two third of people over 65 years has insufficient serum levels of vitamin D (<30 ng/ml). Almost half of them present deficiency (<20 ng/ml), severe in many cases (<15 ng/ml). This proportion increases when we analyze non-white populations, women, and people with obesity, diabetes mellitus or diets poor in Vitamin D. Low serum vitamin D concentration has been linked to mortality, osteoporosis, falls propensity, fractures, frailty, and cardiovascular diseases, including hypertension. Several epidemiological studies open the possibility to a relationship between low levels of the vitamin D and many other diseases. Among them with different cancer, diabetes, some types of dementia, Parkinson's disease, macular degeneration or periodontitis. Also with muscle strength, mobility and physical performance. Vitamin D supplementation has beneficial clinical effects, with a significant reduction of risks, specially in subjects living in nursing-homes and in those treated with corticoids or antireabsortive drugs. These effects are doses dependent. Risk of intoxication is minimal, even with high doses of vitamin.
This article was published in An R Acad Nac Med (Madr)
and referenced in Journal of Osteoporosis and Physical Activity