alexa Vitamin D deficiency rickets in breast-fed infants presenting with hypocalcaemic seizures.


Journal of Community & Public Health Nursing

Author(s): Ahmed I, Atiq M, Iqbal J, Khurshid M, Whittaker P

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Abstract At the Aga Khan Hospital (AKUH), 65 infants presented with hypocalcaemic seizures, subsequently found to have rickets. Forty-six infants less than 6 months were totally or predominantly breast fed. In a subgroup of 15 mothers and their infants, we found very low plasma levels of 25(OH) vitamin D of < 5 micrograms/l and 7.5 +/- 3.3 micrograms/l, respectively. Neither mothers nor infants received vitamin D supplementation. Maternal vitamin D deficiency and non-supplementation in the infants were the likely causes of rickets in our patients. Prophylactic vitamin D 400 i.u. administered to infants up to 2 years and 800 i.u. to women in pregnancy and during lactation is recommended to prevent vitamin D deficiency.
This article was published in Acta Paediatr and referenced in Journal of Community & Public Health Nursing

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