alexa Vitamins and aging: pathways to NAD+ synthesis.


Journal of Aging Science

Author(s): Denu JM

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Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis. In this issue, Belenky et al. (2007) report that nicotinamide riboside, a new NAD(+) precursor, regulates Sir2 deacetylase activity and life span in yeast. The ability of nicotinamide riboside to enhance life span does not depend on calorie restriction.

This article was published in cell and referenced in Journal of Aging Science

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