alexa Vitex agnus-castus (Chaste-Tree Berry) in the Treatment of Menopause-Related Complaints
General Science

General Science

Journal of Research and Development

Author(s): Margaret Diana van Die, Henry G Burger, Helena J Teede, Kerry M Bone

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Background: The origin of the current practice of administering Vitex agnus-castus in menopause-related complaints is uncertain, but appears to be relatively recent. Here we review the evidence for this application of Vitex based on evidence from pharmacological studies and clinical research. Methods: The mechanisms of potential relevance in the context of menopause are explored with reference to the current understanding of the endocrinology and neuroendocrinology of menopause and associated symptoms. Conclusions: We conclude that, while evidence from rigorous randomized controlled trials is lacking for the individual herb in this context, emerging pharmacological evidence supports a role for V. agnus-castus in the alleviation of menopausal symptoms and suggests that further investigation may be appropriate.

This article was published in The Journal of Alternative and Complementary Medicine and referenced in Journal of Research and Development

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