alexa [Waist circumference below metabolic syndrome harmonizing criteria is associated with increased cardiovascular risk].
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Konnov MV, Dobordzhinidze LM, Deev AD, Gratsianski NA

Abstract Share this page

Abstract AIM: To test the hypothesis that waist circumference (WC) just below Joint Interim Statement ([JIS], 2009) abdominal obesity thresholds can be associated with worse risk factors profile than smaller WC. METHODS: In a study of risk factors in families of patients with "premature" coronary heart disease (CHD) we examined 229 persons without CHD with body mass index (BMI) 18.5 kg/m and WC <94 cm (men) or <80 cm (women) (67 spouses [28-62 years] and 162 children [16-37 years]) of probands. Risk factors studied included smoking, BMI, WC, BP, total and high density lipoprotein cholesterol (HDL C), triglycerides (TG), basal serum glucose, diabetes and metabolic syndrome (MS JIS criteria, 2009). High BP was defined as prehypertension (PreHT) or hypertension (HT) and named PreHT/HT. In persons aged 16-17 years we used criteria 4 th report of National High BP Education Program Working Group on High BP in Children and Adolescents, in persons 18 years - 7 th Joint National Committee Report (USA). TG 1.7 mmol/l, serum basal glucose 5.6 mmol/l were defined high, HDL C <1.0 mmol/l (men), <1.3 mmol/l (women) - low. Framingham risk score of cardiovascular disease (CVD) was calculated for persons aged 30 years. Factors associated with various ranges of WC were selected by logistical regression univariate analysis. Odds ratios were compared in 2 groups of WC distribution: top ( 83 cm men, 73 cm women - intermediate [I] WC) vs 2 lower (<83 cm men; <73 cm women) tertiles. Analysis was carried out in 2 age groups according to median age: 16-26 years (n=115, 23.5\% with IWC) and 27-62 years (n=114, 50.0 \% with IWC). RESULTS: Persons aged 16-26 years with IWC had significantly higher risk to have high TG, low HDL C and PreHT/HT than those with smaller WC: odds ratios 7.53 (95\% confidence interval [CI] 1.69-33.6; p=0.008), 3.56 (95\% CI 1.35-9.36; p=0.010) and 2.22 (95\% CI 1.13-4.36; p=0.020), respectively. No significant relationship was found between IWC and registered risk factors in age group 27-62 years. In persons aged 30-62 years (n=90, 51.1\% with IWC) IWC was related to presence of 5\% Framingham risk score: OR vs smaller WC 2.59 (95\% CI 1.01-6.67; p=0.048). CONCLUSION: Among younger consorts and adult children of patients with "premature" CHD persons with WC 83 - <94 cm (men), 73 - <80 cm (women) had worse risk factors profile compared with persons with smaller WC.
This article was published in Kardiologiia and referenced in Journal of Diabetes & Metabolism

Relevant Expert PPTs

Relevant Speaker PPTs

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords