alexa Eswar Shankar | Case Western Reserve University
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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Eswar Shankar

Eswar Shankar Eswar Shankar
Case Western Reserve University
USA
 
Biography

Cancer biologist with 10 years’ experience in academic research. Extensive experience working in small molecules, ligands, and natural compounds as chemotherapeutic agents in prostate, kidney, bladder, breast and ovarian cancers. Strong background in signal transduction, chemoprevention, chemo-resistance and inflammation. Significant contributions include identifying the role of: Protein Kinase C epsilon as a pivotal inhibitor of TRAIL induced cell death in breast cancer, NSC109268 as an agent inducing Cisplatin sensitivity in ovarian cancer, High Fat Diet induced inflammation as a cause for prostate cancer, Survivin/TGF-β/mTORC1 Axis in prostate epithelial cell growth. Key findings demonstrated through 15 peer reviewed publications. Serving as a reviewer for PLOSE ONE, Journal of Cancer Therapy (JCT) and Journal of Cancer Science and Therapy. Previous work experience is in quality assurance in medical device/bulk drug industries from India.

Research Interest

Small molecules, ligands, and natural compounds as chemotherapeutic agents in prostate, kidney, bladder, breast and ovarian cancers. Strong background in signal transduction, chemoprevention, chemo-resistance and inflammation. Significant contributions include identifying the role of: Protein Kinase C epsilon as a pivotal inhibitor of TRAIL induced cell death in breast cancer

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