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Co-author of 40 papers on international journals (total impact factor 168.08; H index, 22) and 107 congress abstracts. Since 1991 he has been involved in research projects granted by EU, Telethon, AIRC, AFM (Association Française contre les Myopathies), CNR, MiUR (COFIN, FIRB, PRIN). Experience in immunofluorescence, immunohistochemistry, cell culture, transfections of mammal cells, luciferase reporter genes, recombinant protein expression, Western-blotting, Northern-blotting, PCR/RT-PCR, ChIP (chromatin immunoprecipitation), EMSA, ELISA, handling of laboratory animals (mouse, rat). He attended an Advanced International Course on Immunofluorescence (1997). Membership: Board of Teachers of PhD in Biology and Experimental Medicine (University of Perugia), Interuniversitary Institute of Myology (IIM; member of the Scientific Committee), European Calcium Society, Società Italiana di Anatomia e Istologia. Selected reviewer for research projects from MIUR, University of Padua (Italy), University Pierre et Marie Curie of Paris (France), Swiss Foundation for Research on Muscle Diseases, and Research Foundation Flanders (FWO; Belgium). Ad hoc reviewer for PLoS ONE, Am J Physiol-Regul Integr Comp Physiol, J Cell Mol Med, Curr Pharm Design, and Int J Immunopathol Pharmacol, Cell Death Disease, Acta Physiol, J Spine, J Appl Physiol. Member of the editorial board of the Journal of Functional Morphology and Kinesiology (ISSN 2411-5142).
The biology and physiology of the calcium-binding protein S100B, with respect to the activities of intracellular and extracellular S100B in nervous and non-nervous cell types, particularly muscle precursor cells;
The role of RAGE (receptor for advanced glycation end-products) and S100B in i) the biology of muscle precursor cells; ii) muscle development, regeneration and atrophy; and, iii) the biology of rhabdomyosarcoma cells.
Intraperitoneal transplantation of microencapsulated Sertoli cells as a treatment to Duchenne’s muscular dystrophy and inflammatory myopathies.
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