OMICS International OMICS International is a scientific organization that drives the progress of research through open access journals and organizes international conferences, The best in science news, commentary, and research. Immunotherapy: Open Access Volume 3, Issue 2 Implications of IL6 Targeting Therapy for Sepsis Sujin Kang, Toshio Tanaka, Kazuya Masuda and Tadamitsu Kishimoto Dynamic Immune Activation Upregulation of Immune Inhibitory Pathways inGastric Cancer Congqi Dai and Jin Li Clinical Implications of AntiCD19 Chimeric Antigen Receptors CAR T CellTherapy in Acute Lymphoblastic Leukemia ALL Ali R Jazirehi1, Tam N M Dinh, Zena Taraporewalla, Jahzeel L Paguntalan and Gary J Schiller Immune Cells As Targets and Tools For Cancer Therapy Katarzyna Tonecka, Zofia Pilch, Kavita Ramji, Bartlomiej Taciak, Lukasz Kiraga, Magdalena Krol, and Tomasz P Rygiel Laparoscopic versus Open Total Mesorectal Excision for Resectable RectalCancer An Updated Metaanalysis of Randomized Controlled Trials MingYang Shen, KeYu Yang and Yong Zhou