alexa Lynch syndrome | Russia | PDF | PPT| Case Reports | Symptoms | Treatment

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Lynch Syndrome

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  • Lynch syndrome

    Pathophysiology
    Lynch syndrome is the familial clustering of colorectal and endometrial cancers. This syndrome is passed in an autosomal dominant fashion within families with defective mismatch repair as the genetic basis for cancer development in these patients.

  • Lynch syndrome

    Statistics
    According to neoplastic MSI, age and family history two new criteria for Lynch's syndrome search in the Russian patients have been offered. Efficacy of the first criterion was 60%, that of the second — 85,7%.

  • Lynch syndrome

    Treatment
    Surgery for Lynch syndrome colon cancer is more likely to involve the removal of more of the colon, since people with Lynch syndrome have a high risk of developing additional colon cancer in the future.

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