Most breast cancers in men are ductal carcinomas. Ductal means the cancer started in the milk pipes of the breast, called ducts. These cancers are usually invasive because they start inside the duct and then break through the wall of the duct, growing into the normal surrounding breast tissue.
Russian bilateral breast cancer patients using an approach based on high-resolution melting analysis and direct sequencing of genomic DNA samples. PALB2 germline mutations account for a small, but not negligible, proportion of bilateral breast carcinomas in German and Russian populations.