(IMN) is a disease in which glomerular basement membrane becomes thickening by light microscopy on renal biopsy and it represents a major cause of primary nephrotic syndrome in adults. The main sign of Membranous Nephropathy is the loss of proteins, primarily , from the blood into the urine(proteinuria).
Someone with membranous nephropathy may discharge several hundreds of milligram of proteins each day, up to more than 10g/24h with advanced kidney disease. rate (GFR) is performed to determine residual . other tests may be done to see how well the kidneys are working, which include blood urea nitrogen, blood creatinine, creatinine clearance test, etc.
In adults the most common disease is mesangiocapillary glomerulonephritis (30-40%), followed by focal and segmental glomeruloesclerosis (15-25%) and minimal change disease (20%). Its main cause is diabetic nephropathy. It usually presents in a patient’s 40s or 50s. Of the cases approximately 60% to 80% are primary, while the remainder are secondary .
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