Intellectual disability (ID), also called intellectual development disorder (IDD) or general learning disability, and formerly known as mental retardation (MR) is a generalized neurodevelopmental disorder characterized by significantly impaired intellectual and adaptive functioning. It is defined by an IQ score below 70 in addition to deficits in two or more behaviors that affect every day, general living.
Pathophysiology: Sometimes disability is caused by abnormal genes inherited from parents, errors when genes combine, or other reasons eg. Down syndrome, Klinefelter's syndrome, Fragile X syndrome (common among boys), neurofibromatosis, congenital hypothyroidism. Intellectual disability can result when the fetus does not develop properly.
Diagnosis: The three criteria must be met for a diagnosis of intellectual disability: deficits in general mental abilities, significant limitations in one or more areas of adaptive behavior across multiple environments and evidence that the limitations became apparent in childhood or adolescence. In general, people with intellectual disability have an IQ below 70, but clinical discretion may be necessary for individuals who have a somewhat higher IQ but severe impairment in adaptive functioning.
The WHO Global Burden of Disease study – which used limited data from the Russian Federation11 – estimated unipolar depression to account for 4% of the country’s total burden of disease in 2002.12 The suicide rate peaked in the mid-1990s, when for men aged 50–54 years this was over six times that seen in the United States of America: 139 and 22.5 deaths per 100 000 population, respectively.