alexa Morphea | Russian Federation| PDF | PPT| Case Reports | Symptoms | Treatment

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Morphea

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  • Morphea

     Morphea, also known as "localized scleroderma", or "circumscribed scleroderma", involves isolated patches of hardened skin with no internal organ involvement. Morphea is most often presents as macules or plaques a few centimeters in diameter, but also may occur as bands or in guttate lesions or nodules. Morphea is a thickening and hardening of the skin and subcutaneous tissues from excessive collagen deposition. Morphea includes specific conditions ranging from very small plaques only involving the skin to widespread disease causing functional and cosmetic deformities.

  • Morphea

     Throughout the years, many different treatments have been tried for morphea including topical, intra-lesional, and systemic corticosteroidsAntimalarials such as hydroxychloroquine or chloroquine have been used. Other immunomodulators such as methotrexate, topical tacrolimus, and penicillamine have been tried. Some have tried prescription vitamian-D with success. Ultraviolet A (UVA) light, with or without psoralens have also been tried. Morphea prevalence rate of 158,794 for populations of 143,974,0592 is seen in Russia.

 

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