Polyps are an end result of varying disease processes in the nasal cavities. Conditions leading to chronic inflammation in the nasal cavity such as bronchial asthma can lead to nasal polyps.Out of 30,987 telephone calls made to the households, 44% (1,610/3,671) had experienced nasal symptoms and 20% (734/3,671) had been formally diagnosed with AR, nasal allergies, or hay fever by a physician. Among the subset of cooperative respondents asked further about specific comorbid conditions, 27% reported asthma, 17% reported having been diagnosed with chronic or recurrent sinusitis (n=1,595 respondents queried) and 5% had nasal polyps (n=1,591 respondents queried).
Oral steroids are the most effective medical treatment for nasal polyposis. In adults, most authors use prednisone (30-60 mg) for 4-7 days and taper the medicine for 1-3 weeks. Dosage varies for children, but the maximum dose is usually 1 mg/kg/d for 5-7 days, then taper over 1-3 weeks.Based on current data, the evidence for efficacy of available anti-IgE and anti-IL-5 antibodies on the market is very low, and more studies are needed in order to recommend their use in the treatment of CRSwNP patient