A total of 18 patients with osteomyelitis aged from 18 to 61 years were treated with cell transplants.Osteomyelitis is an inflammatory process localized in bone tissues and bone marrow. Nowadays the greatest importance is given to hematogenous osteomyelitis, which is predominantly found in children (85%). Acute osteomyelitis was simulated in 30 infants rabbits aged 3-4 months whose body weight accounted 1200-1600 grams through the insertion of 5-6 million of aurococcus into the marrow channel of a shinbone. The gems were inserted together with 0.5 ml of acetylated collagen suspension (10mg/ml) and physiological saline of sodium chloride.
The animals were taken out of the experiment after 30 minutes, 6, 12, 24, 48 and 60 hours after the contamination correspondently to perform histological research of shinbones and surrounding soft tissues. Most well-established bone infections are managed through open surgical procedures during which the destroyed bone is scraped out. In the case of spinal abscesses, surgery is not performed unless there is compression of the spinal cord or nerve roots. Instead, patients with spinal osteomyelitis are given intravenous antibiotics. After surgery, antibiotics against the specific bacteria involved in the infection are then intensively administered during the hospital stay and for many weeks afterward.