Paget’s disease of bone is a chronic disease of the skeleton. Normally it grows on the bone and makes the bone breaks or bones can grow larger than before. Bone consists of osteoblasts, Osteoclasts, Ostecytes, Matrix. Paget's disease may affect up to 3% of adults older than 40 years. It is often asymptomatic and usually progresses slowly. Once in a while, it can form into an essential bone malignancy known as Paget's sarcoma. Regularly Paget's ailment is limited to just a couple bones in the body.
Chondrosarcoma is the most frequently occurring bone sarcomas of adulthood. The incidence is about 0.2/100 000 per year, with the most common age at diagnosis being between 30 and 60 years and the male–female ratio is ∼1.
Although initially diagnosed by a primary care physician, Endocrinologists (inward medication doctors who have some expertise in hormonal and metabolic issue), rheumatologists (inside pharmaceutical doctors who represent considerable authority in joint and muscle issue), orthopedic specialists, neurosurgeons, neurologists, oral and maxillofacial specialists, podiatrists, and otolaryngologists are by and large learned about treating Paget's malady, and may be called upon to assess particular indications. The goal of treatment is to relieve bone pain and prevent the progression of the disease.