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Pediatric Thrombocytopenia

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  • Pediatric thrombocytopenia

    Pathophysiology

    Pediatric Thrombocytopenia is a condition in which you have a low blood platelet count. Platelets (thrombocytes) are colorless blood cells that help blood clot. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries. Thrombocytopenia often occurs as a result of a separate disorder, such as leukemia or an immune system problem. Or it can be a side effect of taking certain medications. It affects both children and adults. Thrombocytopenia may be mild and cause few signs or symptoms. In rare cases, the number of platelets may be so low that dangerous internal bleeding occurs. Treatment options are available.

  • Pediatric thrombocytopenia

    Disease statistics

    Thrombocytopenia is common in mothers and newborns and usually is caused by an increased rate of platelet destruction. The reference range of a normal platelet count in nonpregnant women and newborns is 150,000-400,000/µL; however, mean platelet counts in pregnant women generally are lower.

  • Pediatric thrombocytopenia

    Treatment

    Specific treatments for thrombocytopenia will be determined by your child’s physicians based on the cause and severity of the disease, as well as your child’s tolerance for medications, procedures and therapies. Mild cases may not require treatment and may resolve on their own. Blood transfusions with platelets or red blood cells are sometimes needed.

  • Pediatric thrombocytopenia

    Research

    Strategies for providing platelets for alloimmune thrombocytopenia vary by institution and your blood bank physician should be consulted for assistance

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