Preeclampsia is a disease mainly occurs in pregnant ladies. This disease characterized by high blood pressure and it also damages the other organs of the body. This Preeclampsia disease usually starts after 20-25 weeks of pregnancy in a woman whose blood pressure is in normal stage. Even for simple complications in blood pressure may be a sign of Preeclampsia. Left untreated, preeclampsia can lead to serious — even fatal — complications for both you and your baby. If you have preeclampsia, the only cure is delivery of your baby. If you're diagnosed with preeclampsia too early in your pregnancy to deliver your baby, you and your doctor face a challenging task. Your baby needs more time to mature, but you need to avoid putting yourself or your baby at risk of serious complications.
Sometimes Preeclampsia may develop without any symptoms. High blood pressure may develop slowly, but more commonly it has a sudden onset. Monitoring your blood.
Treatment: The main cure for preeclampsia is only delivery. You're at increased risk of seizures, placental abruption, stroke and possibly severe bleeding until your blood pressure decreases. Of course, if it's too early in your pregnancy, delivery may not be the best thing for your baby. If you're diagnosed with preeclampsia, your doctor will let you know how often you'll need to come in for prenatal visits — likely more frequently than what's typically recommended for pregnancy. You'll also need more-frequent blood tests, ultrasounds and nonstress tests than would be expected in an uncomplicated pregnancy. Possible treatment for preeclampsia may include: Medications to lower blood pressure, Corticosteroids, Anticonvulsant medications
Statistics: In Russia, the survey of Preeclampsia was, in preeclamptic umbilical arteries, the expression of Fli-1, a transcription factor and a negative regulator of fibrosis, was significantly reduced (P<0.001), whereas procollagen-1 expression was increased (P<0.01). As compared to control vessels, isolated rings of umbilical arteries from patients with preeclampsia demonstrated unaltered responsiveness to endothelin-1 (EC50=2.2 and 3.2 nmol/l, respectively), but exhibited an impaired response to the relaxant effect of sodium nitroprusside (EC50=1.5 vs. 32.4 nmol/l, P<.001) following endothelin-1-induced constriction. Ex-vivo treatment of normal umbilical arteries explants with 1 and 10 nmol/l MBG for 24 h mimicked the effects of preeclampsia, specifically suppressed Fli-1 and increased collagen-1 expression while impairing vasorelaxation.