alexa Trigeminal neuralgia | Russia | PDF | PPT| Case Reports | Symptoms | Treatment

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Trigeminal Neuralgia

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  • Trigeminal neuralgia

    Trigeminal neuralgia (TN), also known as tic douloureux, is a common and potentially disabling pain syndrome, the precise pathophysiology of which remains obscure. This condition has been known to drive patients with trigeminal neuralgia to the brink of suicide. Although neurologic examination findings are normal in patients with the idiopathic variety, the most common type of facial pain neuralgia, the clinical history is distinctive. The fact that TGN pain is not continuous but paroxysmal speaks against a simple compression induced generation of ectopic impulses at the level of the injury. It is more likely that the paroxysms of pain in this condition represent spontaneous discharges in select neurones whose threshold for repetitive firing has been altered. To comply with the characteristics of TGN, such firing should not only occur spontaneously but be produced frequently by innocuous tactile stimuli. Depression is often seen in patients with trigeminal neuralgia; thus, this underlying depression should be adequately treated. Tricyclic antidepressants (eg, amitriptyline, nortriptyline), as well as sodium valproate or pregabalin, have not been well studied. Amitriptyline (Elavil) can be tried, but the success rate is low. Russia people around 1,644,960 among the total population are suffering from this disease that is 4.68% of the population effected.

 

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