Pathophysiology: Whipple´s disease is caused by chronic infection with the bacterium Tropheryma whipplei. T whipplei appears intra- as well as extracellulary and can be detected by a PAS-staining of intestinal biopsies within infected macrophages, indicated by a deep red colour representing the bacteria or parts of their cell walls.
Disease statistics: This page presents a variety of statistics about Whipple's Disease. The term 'prevalence' of Whipple's Disease usually refers to the estimated population of people who are managing Whipple's Disease at any given time. The term 'incidence' of Whipple's Disease refers to the annual diagnosis rate, or the number of new cases of Whipple's Disease diagnosed each year.
Treatment: Whipple’s disease is a bacterial infection that can lead to death if not treated properly. You will normally be on daily antibiotics for one to two years. Taking antimalarial medication for 12 to 18 months, using iron supplements to assist with anemia, taking vitamin D, vitamin K, calcium, and magnesium supplements, maintaining a high-calorie diet due to lack of nutrient absorption, taking corticosteroids to help ease inflammation.
Research: The NINDS supports research on disorders that affect the central nervous system such as Whipple's disease. The National Institute of Diabetes and Digestive and Kidney Diseases also support research on disorders such as Whipple's disease. Much of this research is aimed at learning more about these disorders and finding ways to prevent, treat, and, ultimately, cure them.