alexa Abstract | A Rare Case of Focal Segmental Glomerulosclerosis in a Patient with Grade a Benign Thymoma: A Case Report and Review of the Literature
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report Open Access

Abstract

Thymoma is a rare mediastinal tumour that is often (40%) accompanied by different paraneoplastic syndromes and glomerulonephritis is one of the recognized entities. Minimal change disease is the most common paraneoplastic glomerulonephritis associated with thymoma, followed by membranous nephropathy, focal segmental glomerulosclerosis, rapidly proliferative glomerulonephritis and lupus nephritis. Literature review illustrates that most of the thymoma associated nephropathy cases were reported in association with more malignant thymic tumors like WHO grade B and C tumours. Herein we report a rare case of focal segmental glomerulosclerosis in a patient with grade A benign thymoma, a combination which has never been reported previously. She had poor response to corticosteroids and died due to neutropenic sepsis following azathioprine therapy.

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Author(s): Prashan Buddhika Illeperuma and Ananda Jayanaga

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