alexa Abstract | A Case of Mandibular Tumour in a Skull from an Early Modern Cemetery in Wroclaw, Poland

Annals of Clinical and Laboratory Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Background: The objective of our study was to diagnose a case of non-malignant bone tissue malformation in an adult female, located in the midline of the mandibular body, as a part of skeletal material excavated from the Early Modern cemetery in Wroc?aw.

Methods and Findings: The macroscopically identified tumour-like hyperplastic lesion was examined using radiographic imaging techniques but also analysed for histopathological features. We identified signs of periosteal reaction and irregular growth of bone tissue which macroscopically resembled a spongy structure. The recorded image shows an irregular hyperplasia of bone lamellae, formed on the inner side of the mandibular corpus, causing secondary changes in the normal structure of the compacted bone and partly in spongy bone. Both techniques confirmed that this condition is most characteristic of a neoplastic lesion, defined as osteoma spongiosum.

Conclusions: Growing tumour finally caused a massive deformation of the alveolar part of the mandible. The immediate consequence of such overgrowth of bone tissue was probably the intravital loss of incisors and change of occlusion affecting periodontal health. Therefore it could have significantly deteriorated the quality of life of the studied individual. The identified mandibular osteoma spongiosum is the first case of this type reported for the historic area of Wroc?aw. We believe that information on neoplastic disorders of bone in archaeological skeletal materials, when properly diagnosed and described, may be an important contribution to epidemiological studies on neoplastic diseases among ancient and contemporary human populations.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Pawel Dabrowski Stanislaw Gronkiewicz Tomasz Staniowski Klaudiusz Luczak Katarzyna Staszak and Bohdan Gworys


Mandibular tumour, Bone hyperplasia, Osteoma spongiosum, Biomarker Research, Clinical Laboratory Research, Brain tumor

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version