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Short Communication Open Access
Cellulose acetate microcapsules of indomethacin and diclofenac were prepared by emulsification - coacervation (Ec) and emulsification-solvent evaporation (ESE) methods. Microcapsules prepared by ESE method were denser, less permeable, and showed slower release than those prepared by EC method. In both the cases drug release depended on wall thickness and size of the microcapsules and followed first order kinetics.
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Author(s): K P R Chowdary K Siva Rama Prasad