alexa Abstract | A Comparative Study of the Anthelmintic Potential of Cleome Viscosa L. and Cleome Burmanni W. and A.

Indian Journal of Pharmaceutical Sciences
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Methanol, aqueous and chloroform extracts of Cleome viscosa and Cleome burmanni were tested for anthelmintic potential against the Indian earthworm Pheritima posthuma. Different concentrations of the extracts ranging from 50-2000 µg/ml were tested and results expressed as time required for paralysis and death of the worms. Piperazine citrate was used as a reference standard and DMSO (1%) as the negative control. The methanol extracts of Cleome viscosa and Cleome burmanni exhibited significant anthelmintic activity. Methanol extract of Cleome viscosa at a concentration of 2000 µg/ml was detected to be the most effective treatment dose. Thin layer chromatography of methanol extracts of both plants revealed the presence of terpenoids.

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Author(s): Lakshmi S Pillai Bindu R Nair


Anthelmintic activity, Cleome viscosa, Cleome burmanni, DMSO, Pheritima posthuma, piperazine citrate, terpenoids

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