alexa Abstract | A green alternative approach for synthesis of 2-substituted-1H-Perimidine catalysed by NBS in Ultra Sonication method

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


An expeditious and greener one-pot procedure was developed for the synthesis of 2-substituted-1H-perimidine derivatives. In the presence of catalytic amount of NBS, aldehydes and 1,8-diaminonaphthalene were converted into the corresponding 2-substituted-1H-perimidine derivatives in moderate to high yields under sonication. Highly efficient and simple methods have been described in this manuscript for the synthesis with competent yields. Present synthesis complies with principle of Green chemistry. As part of current studies, we here in report economical practical techniques like ultrasonic wave organic synthesis and by application of green solvents. On completion of reaction the products were characterized by IR, NMR and Mass Spectra. These methods are more convenient and reactions can be carried out in higher yield (94-97%), shorter reaction time (08mins-20mins) and milder conditions, without generation of pollution and safer to analyst.

To read the full article Peer-reviewed Article PDF image

Author(s): M Hari Krishna and P Thriveni


Ultrasonic irradiation, Green chemistry, N-Bromosuccinamide (NBS), perimidine, Ecofriendly, Efficient, 2-substituted-1H-Perimidine

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version