alexa Abstract | A New Perspective on the Use of Phaleria macrocarpa in the Management of Cardiovascular and Metabolic Diseases: A Research Review

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

Phaleria macrocarpa is one of the plants originating from Indonesia that has been empirically known for its medicinal properties. The medicinal properties have also been scientifically revealed for the management of conditions related to chronic diseases, including hyperglycemia, dyslipidemia and renal disorders. With regards to increased blood glucose, studies have proven that P. macrocarpa helps to lower blood glucose levels. These studies have proven that P. macrocarpa helps to lower blood glucose levels by reducing the activity of α-glucosidase, an enzyme involved in the digestion of carbohydrate, thus further reduced the rate of glucose absorption. P. macrocarpa treatment was also able to significantly improve blood lipid profiles and its related parameters, including total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride. It also showed improvements in genes and proteins that are associated to the regulation of cholesterol transport and homeostasis, including LDL-R, PCSK9 and CETP. Nephroprotective effect of P. macrocarpa was revealed by reduction in VEGF and TGF-α that are known to regulate angiogenic and cells proliferation. Effects of P. macrocarpa through various parameters and pathways making it highly favorable to be developed as the treatment of cardiovascular and metabolic diseases risk factor, especially in managing hyperglycemia, dyslipidemia, as well as protecting the kidneys

To read the full article Peer-reviewed Article PDF image

Author(s): Isabela Anjani and Raymond R Tjandrawinata

Keywords

Phaleria macrocarpa, hyperglycemia, dyslipidemia, diabetes, cardiovascular, Phaleria macrocarpa

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords