alexa Abstract | A New Reverse Phase High Performance Liquid Chromatographic Method For Analysis Of Rofecoxib In Tablets

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access


A simple, selective, rapid, precise and economical reverse phase HPLC method has been developed for the determination of rofecoxib in tablets. The analyte is resolved by using a mobile phase (methanol and water in the ratio 50:50) at a flow rate of 1 ml/min on an isocratic HPLC system (Shimadzu) consisting of LC 10AT liquid pump, SPD 10A UV-Visible detector, a ODS C-18 RP column (4.6 mm I.DX25 cm) at a wavelength of 230 nm. The linear dynamic range for rofecoxib was 2-40 μg/ml by this method. Paracetamol was used as an internal standard.

To read the full article Peer-reviewed Article PDF image

Author(s): K E V Nagoji S Vijayasrinivas M Kiran Kumar N Mathivanan M Satish Kumar M E B Rao

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version