alexa Abstract | A Quantitative Structure - Activity Relationship Analysis Of Some Substituted Oxazolopyridines And Benzimidazoles With Antiinflammatory Activity

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access

Abstract

The lowest energy conformations of some antiinflammatory 2-(substituted phenyl) oxazolopyridines, 2-(substituted pyridinyl) benzimidazoles and 1H-benzimidazoles were calculated and quantitative structure-activity relationship analysis was then performed on each category of compounds using thermodynamic, electronic and spatial descriptors. The resulting QSAR equations were validated by leave-one-out cross validation method. Electronic parameter (dipole moment) and spatial parameters (molecular volume and principal moment of inertia) were found to have significant correlationship with antiinflammatory activity.

To read the full article Peer-reviewed Article PDF image

Author(s): S K Chakravarti S C Chaturvedi

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords