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Fanconi’s syndrome (FS) is a disease of proximal renal tubule with inherited or acquired etiology. Nucleotide reverse transcriptase inhibitors (NtRTIs) are well known causes of this entity. Tenofovir is one of the safest drug in this group, successfully used in HIV and Hep B infected patients. Case reports have shown FS occurring at the initiation of therapy and recommend renal function and electrolyte monitoring up until 18 months1. We present a case of Fanconi’s Syndrome in an HIV patient occurring more than 6 years after starting Tenofovir therapy.
renal tubular acidosis, nephrotoxicity, Fanconiâs syndrome, Tenofovir