alexa Abstract | An extractive econometric method for the determination of dothiepin hydrochloride from pharmaceutical preparations.

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


An extractive colorimetric method for the determination of dothiepin hydrochloride from pharmaceutical preparations is described. The method is based on the formation of ion-pair complexes of the drug with reagents like bromophenol blue (BPB), bromothymol blue (BTB), bromocresol purple (BCP) and bromophenol red (BPR) in acidic medium. The ion-pair complexes formed are quantitatively extracted in chloroform. The method is statistically validated and is found to be precise and accurate.

Author(s): RT Sane RM Kothurkar KD Ladage RV Tendolkar DP Gangal

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