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The present study was aimed to develop and validates for the analysis of Drotaverine HCl in bulk and tablet formulation. Drotaverine HCl in presence of acidic medium reacts with excess amount of potassium bromide bromate with crystal violet and oxidizes crystal violet. It shows the absorbance at 590nm.The Beer’s law was obeyed in the concentration of 10-60mcg/ml. The method was validated for linearity, accuracy, precision and ruggedness. Proposed method was Statistically validated by recovery studies.
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Author(s): Prabhu Padmavathi P Paramita Das Panara Krunal EVSSubrahmanyam
Drotaverine hydrochloride, Potassium bromide bromate, Crystal violet, Beer’s law