alexa Abstract | Anti- histamine effect of hydroalcoholic extract of Andrographis Paniculata leaf (Burm. F)

Der Pharmacia Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Andrographis paniculata has obtained a well renowned name as one of the best traditional remedies, owing to its multiple pharmacological activities. In this work, the anti- histamine effect of hydroalcoholic leaf extract of Andrographis paniculata (Burm.f), family Acanthaceae, was planned. The concentration response curve (CRC) of histamine was recorded and its modification by anti histamine drugs of pheniramine maleate and hydroalcoholic extract of Andrographis paniculata Leaf (1mg/ml) by using guinea pig ileum preparation. The histamine dose responses were reduced (*P<0.005) after the incubation of hydroalcoholic extract of Andrographis paniculata Leaf (1mg/ml) when compared with normal CRC of histamine. The CRC of histamine was reduced (*P<0.05) after the incubation of pheniramine maleate (100μg/ml) when compared with normal CRC of histamine. The pheniramine maleate has been highlighted more anti histamine activity when compared with Andrographis paniculata leaf extract (APLE). Hence our present study was aimed to justify that the traditional claim of the entire leaf has used against histamine induced disease condition.

To read the full article Peer-reviewed Article PDF image

Author(s): M Karpakavalli G Nagaraja Perumal V E Ida Christi M Dhanamani S Uma maheswara Rao

Keywords

Andrographis paniculata (Burm.f), antihistaminic activity, pheniramine maleate

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords