alexa Abstract | Antibacterial activity of crude extracts and fractions from Iranian wild-grown and cultivated Agaricus spp.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Agaricus species are among the most important commercial mushrooms in the world. Thus far, antibacterial activities of several Agaricus spp. have been reported. However, no study was undertaken to evaluate antibacterial activities of Iranian wild Agaricus spp. In addition, the information about compounds conferring antibacterial activity in these species is scarce. The aim of this study was to determine the antibacterial activity of methanol-dichloromethane (1:1) extracts of several wild and cultivated species of Agaricus through a colorimetric micro-dilution method. In addition, several active fractions obtained from the crude extract of cultivated A. bisporus was assayed for antibacterial activity. The findings revealed that the mushroom crude extracts showed quantifiable inhibition only towards the Gram-positive bacteria. The cultivated A. bisporus significantly exhibited higher antibacterial activity than did the wild strain, even though no complete inhibition was observed. In addition, A. devoniensis and A. gennadii exhibited slight inhibitory effects against only Staphylococcus aureus. Six different fractions were then eluted from the crude extract of cultivated A. bisporus through a step wise gradient elution, of which two fractions exerted quantifiable antibacterial activities. As opposed to the crude extract, these two fractions significantly inhibited both the Gram-positive and the Gram-negative bacteria particularly E. coli at 8 mg/ml. These fractions might promisingly possess bioactive compounds and warrant further investigations to develop new antimicrobials obtained from A. bisporus.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Hadi Soltanian Sharareh Rezaeian Abolfazl Shakeri Javad Janpoor Hamid R Pourianfar



Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version