alexa Abstract | Anticancer activity of a constituent from Moringa oleifera leaves

Journal of Chemical and Pharmaceutical Research
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Original Articles Open Access

Abstract

A new long-chain glucoside was isolated from methanolic extract of Moringa oleifera leaves and identified as b-Dglucopyranosidetetradecanoate along with b-sitosterol and b-sitosterolglucoside. b-sitosterolglucoside was first report from this plant. Cytotoxicity bioassay against four human cancer lines was carried out. The compound exhibited good activity against colon cancer cell line (Colo-320 DM) with IC90 value of 3.98. The compound showed moderate to low activity against other 3 cell lines (PA-1, MCF-7 and KB-403).

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Author(s): H Kaur and Shantanu

Keywords

Moringa oleifera,b-D-glucopyranosidetetradecanoate, Cytotoxicity, Colo-320 DM, PA-1, MCF-7 and KB-403, Anticancer activity

 
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