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Research Article Open Access
Anticonvulsant activity was studied against maximal electroshock (MES) and Pentylenetetrazol (PTZ) induced convulsions in mice. The extract suppressed hind limb tonic extensions (HLTE) induced by MES and also exhibited protector effect in PTZ-induced seizures. In conclusion, we showed that the ethanolic extract of Cynodon dactylon has anticonvulsant effect in the both models, suggesting their possible depressant action in the central nervous system.
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Author(s): Vipin K Garg and Sarvesh K Paliwal
Cynodon dactylon, anti-convulsant activity, maximal electro shock, pentylenetetrazole