alexa Abstract | Antidiabetic activity of Poterium sanguisorba L. extract on streptozotocinnicotinamide induced diabetic rats

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

Diabetes mellitus is one of the most progressive disease in the world especially type 2. It is known that injection of streptozotocinin terms of previous injection of nicotinamidecauses the main metabolic violations of diabetes mellitus type 2 in rats. The aim of our study was to evaluate the effect of Poterium sanguisorba extract on body weight, blood glucose, plasma insulin and lipid profile in streptozotocin-nicotinamide induced diabetic rats. Our results showed that in streptozotocin-nicotinamide induced diabetic rats were observed weight loss, decreased insulin sensitivity, hyperinsulinemia, increased insulin resistance coefficient, increased lipid profile and atherogenic index. Poterium sanguisorba extract was able to improve insulin resistance, glucose toleration, rectifies dyslipidemia in streptozotocin-nicotinamide induced diabetic rats.

To read the full article Peer-reviewed Article PDF image

Author(s): Viktoriia Klevanova and Sergiy Trzhetsynskiy

Keywords

Poterium sanguisorba L., Blood burnet, insulin resistance, streptozotocin, nicotinamide, rats, Antidiabetic activity

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us