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Short Communication Open Access
The petroleum ether and chloroform extracts of the roots of Cyclea burmanni (Fam. Menispermaceae) have been found to possess significant antifertility effect in rats. Both these extracts exhibited partial and complete resorption of implants at 200 and 400 mg/kg body weight dose levels. In estrogenic activity study, both the extracts increased uterine weight and caused opening and cornification of vagina in immature rats. The present work justifies its effectiveness in preventing pregnancy in all rats when administered at 400 mg/kg p.o.
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Author(s): SK Panda SK Sahu GK Dash