alexa Abstract | Anti-oxidant and anti-inflammatory activity of synthesized 3-substituted schiff bases of quinazoline 2, 4-diones

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


3-Substituted Schiff bases of Quinazolne-2,4-diones which belongs to the N-containing heterocyclic compounds. The aim of the present study is to study pharmacological study of 3-Substituted Schiff bases of Quinazoline2,4-diones. In the current course of work the novel Schiff bases of Quinazolne-2,4-diones have been synthesized and evaluated for Anti-oxidant and In vitro anti-inflammatory study. 3-Substituted Schiff bases of Quinazoline 2,4-diones have been evaluated for Antioxidant and anti-inflammatory activity. Antioxidant activity was evaluated by Ferric reducing antioxidant power (FRAP), 1,1-DPPH(2,2-diphenyl-1-picrylhydrazyl) And anti-inflammatory activity by membrane stabilization method. The newly synthesized compound F and I showed highest anti-oxidant activity .This compound was further evaluated for in-vitro anti-inflammatory activity by membrane stabilization method. The result of the present study thus demonstrates the anti-inflammatory and anti-oxidant activity of newly synthesized 3-Substituted Schiff bases of Quinazolne-2, 4-diones.

To read the full article Peer-reviewed Article PDF image

Author(s): Deepali Gangrade and Sayali Lad


Schiff base, Quinazoline 2,4-diones, Antioxidant, Anti‐inflammatory, Ferric reducing antioxidant power (FRAP),1,1-DPPH, membrane stabilization method, Anti-oxidant

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version