alexa Abstract | Anti-Oxidative and Anti-Metalotoxic Properties of Green Tea Catechin: A Preliminary Study

American Journal of Ethnomedicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Aim of the study: Green tea catechin possesses antioxidant and free radical scavenging activity which stimulate detoxification system through selective induction or modification of phase I and phase II metabolic enzymes. This study was carried out to assess the anti- oxidative and anti- metalotoxic effect of green tea Catechin against cadmium chloride in mice.
Method: Adult Swiss albino mice were intoxicated with different doses of cadmium chloride in the presence (experimental) or absence (control) of green tea Catechin. Dose selection and DRF of Catechin were studied. The optimum dose of Catechin was determined by administering 1000, 1500, 2000, 5000, 7500μg/ k.g./ animal/ day of Catechin consecutively for 15 days, thence antioxidant enzymes (superoxide dismutase, catalase, & glutathione peroxidase), Phase I enzymes (Cytochrome P- 450 & Cytochrome b5), Phase II enzymes (Glutathione S- transferase & DT- diaphorase), antioxidant molecule (reduced glutathione) and lipid per- oxidation level were estimated in testes, liver and blood after 24 hrs, 7th day 16th and 31st day of Catechin administration.
Results: The dose of Catechin found to be most effective was 7500 μg, because this dose significantly increased the of Phase I & II enzymes, antioxidant parameters and decreased lipid per- oxidation. On the basis of survival data of mice DRF of Catechin against cadmium chloride was evaluated as 1.61. Conclusion: From the present results, it is evident that the green tea Catechin has the potential to reduce deleterious effects of cadmium chloride in mammals.

To read the full article Peer-reviewed Article PDF image

Author(s): Priyanka Sharma Pradeep K Goyal


Cadmiunm chloride, Catechin, Phase I & II enzymes, Antioxidant, Swiss albino mice, Antibacterial, Antioxidant, Antioxidants, Ethnobotanical devices, Ethnobotany Ethnomedicinal plants, Ethnomedicine, Gingee hills, Herbal medicine, Hillocks, Medicinal plants, Nigella sativa, Phytochemical Phytochemicals, Piper guineense, Plasmodium falciparum, Rheumatoid arthritis, Traditional, Traditional knowledge, Tribes

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version