alexa Abstract | Antistaphylococcal synergistic interaction between the essential oil of RosmarinusofficinalisL.and ciprofloxacin

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

This work is , in addition to the p hytochemical study , to evaluate the anti - staphylococcal activity of the essential oil of Rosmarinus officinalis L. and detect some kind of synergy interactions with c iprofloxacin. Essential oil is extracted by steam distillation in a Clevenger type apparat us (Clevenger, 1928), analyzed by gas chromatographic coupled with mass spectrometry. Aromatogram , minimum inhibitory concentrations (MIC ) and bactericidal (MBC ) allowing to evaluate the anti - Staphylococcus aureus activity of essential oil alone or in com bi nation with ciprofloxacin were studied . The report MBC/ MIC of the essential oil of rosemary is 1, which allows the oil to qualify as a bactericide . Ciprofloxacin is bactericidal with a report MB C/ MIC equal to 2, which confirms the summary of the charact eristics of this product. The MICs of the two products are used to calculate the fractional inh ibitory concentration (FIC) , it is less than 1 , which is used to identify a synergistic interaction between ciprofloxacin and the essential oil of rosemary . Int eraction between the essential oil of Rosmarinus officinalis L. and ciprofloxacin is synergistic. It may enhance the anti - S taphylococcal activity and reduce the number and severity of side effects of this fluoroquinolone ; especially those that are dose - dep endent.

To read the full article Peer-reviewed Article PDF image

Author(s): Hakim El Alama AchaEl Aissami Amal Ait Haj Said and FatimaEzzahra El AlaouiFaris

Keywords

Antibacterial activity, synergy, Staphylococcus aureus, essential oil, Rosmarinus officinalisL., ciprofloxacin., Antistaphylococcal , RosmarinusofficinalisL, ciprofloxacin

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us