alexa Abstract | Antiulcer And Gastric Acid Inhibitory Activity Of ZD 7114, A β3-Adrenoceptor Agonist In Rats

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access

Abstract

The antiulcer activity of ZD 7114, aβ3, - adrenoceptor agonist was studied in aspirin plus pylorus ligation induced gastric ulcer in rats and its effect on continuous acid secretion was also studied against in vivo as well as in vitro models. For comparison, the effect of isoprenaline and salbutamol was studied simultaneously in all experimental models. In gastric ulcer model, β-adrenoceptor agonists at all doses were found to be highly effective in affording gastroprotection. ZD 7114 treatment caused significant reduction in acid secretion in vivo model whereas no significant change was observed in vitro model of continuous acid secretion. In contrary to this no significant change in acid secretion was observed by treatment with isoprenaline and salbutamol in vivo model and a significant rise in acid secretion in vitro model.

To read the full article Peer-reviewed Article PDF image

Author(s): A Paul S Patel R Sevak Sunita Goswami D D Santani

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords