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Research Paper Open Access
Dispersible tablets of cyproheptadine-HCI were prepared according to three component simplex optimization technique. Disintegration time of seven batches of the tablets in distilled water was determined. A polynomial equation for computing disintegration time based on simplex design is generated. The application of the equation is demonstrated for predicting disintegration time for a extra-design check point. A contour plot of the results based on the experiment is also presented.