alexa Abstract | Assay Of Lacidipine In Tablets By Extraction Spectrophotometry

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access

Abstract

Three simple spectrophotometric methods for the analysis of lacidipine in pure form or in tablets have been developed based on the formation of chloroform soluble ion associates under specific experimental conditions. Three acidic dyes, tropaeolin 000 (method A), bromocresol green (method B) and azocarmine G (method C) were utilized. The extracts of ion associates exhibited absorption maxima at 420, 500 and 540 nm for methods A, B and C, respectively. Good agreement with Beer's law was found in the range of 10-60 μg/ml (method A), 10-60 μg/ml (method B) and 10-70 μg/ml (method C). These methods are simple, precise and accurate with excellent recovery of 98-102% and also do not require any separation of soluble excipients in tablets. The results obtained are reproducible with coefficient of variation of less than 1.0%.

To read the full article Peer-reviewed Article PDF image

Author(s): G Vidya Sagar N V S Gangadhara Rao B S Sastry

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us