alexa Abstract | Assessment of Serum Calcium, Phosphorus, Creactive protein and Procalcitonin in Tuberculosis Patients

International Journal of Collaborative Research on Internal Medicine & Public Health
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Introduction: Procalcitonin (PCT), a 116 amino acid is the prohormone precursor of calcitonin, is expressed primarily in C-cells of the thyroid gland and to a smaller extent in neuroendocrine tissue of other organs, such as lungs and intestines. PCT is a marker of inflammatory response to infection. C-reactive protein (CRP) is a widely used marker for diagnosis of infections.

Objective: The purpose of our study was to assess the levels of serum PCT, CRP, calcium and phosphorus in patients with pulmonary tuberculosis.

Method: Forty patients diagnosed with tuberculosis were recruited from The Institute of Thoracic Medicine, Chennai, India and compared with age- and sex-matched healthy volunteers (n=40). Serum procalcitonin concentration was analyzed using semi-quantitative PCT-Q kit (B.R.A.H.M.S Diagnostica GmBH, Germany). According to standard procedures, CRP level was determined by immunoturbidimetic assay, calcium and phosphorus by photometric Arsenazo III and phosphomolybdate methods respectively.

Results: Levels of PCT in 27 out of 40 healthy volunteers was <0.5 ng/dl, 3 showing >2 ng/dl. However, 15 out of 40 patients had PCT >2 ng/dl and 25 had PCT>10 ng/dl. CRP levels was significantly elevated in TB patients (p<0.001); Calcium and phosphorus were significantly decreased (p<0.001and p<0.01 respectively) when compared to healthy

Conclusion: Several studies have reported that PCT values were not significantly elevated in TB patients, the contrary results in this study calls for further research on PCT in TB based on the differences in severity of the disease.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Rohini K Srikumar P S Jyoti Saxena Mahesh Kumar A Surekha Bhat


Procalcitonin, CRP, Tuberculosis, Calcium, Phosphorus, Infection

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version