alexa Abstract | Association between Lactobacillus species and bacterial vaginosis-related bacteria, and bacterial vaginosis scores in small population of pregnant Latvian women

International Journal of Collaborative Research on Internal Medicine & Public Health
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Background: One of the most common reasons why females attend doctor are vaginal infections. Vaginal flora is a dynamic environment where a great variety of microorganisms exist in homeostasis. The main normal flora inhabitants are Lactobacillus species who protect from pathogens. Still the majority of factors remain unclear about this genteel environment and its interaction. Aim & Objectives: to analyze vaginal microflora types and microbial species in pregnant women, who were at their first trimester, using PCR and Nugent score diagnostic methods. Methods: 65 pregnant women before their 12th week of pregnancy participated in this study from 06.08.2012 till 31.01.2013. All participants were divided in to 2 groups, group A (n=45) normal pH and group B (n=20) pH ( ≥4,5). Their vaginal fluid were analysed with Nugent score and PCR methods. Results: Genus Lactobacillus (any Lactobacillus) was detected by PCR in all women irrespective of Nugent score, most common species were L. crispatus, L. jensenii, and L. inners, less common were L. gasseri, L. plantaris, L. rhamnosus and L. reuteri. G. vaginalis was present in both patient groups divided by pH but it was significantly higher in bacterial vaginosis and intermediate flora group detected by Nugent score and group B (high pH group). Megasphaera, Leptotrichia/Sneathia were detected more common in pathogenic flora than normal flora. A. vaginae finding was associated with pathologic flora. Conclusion: The most common isolated species in pregnant women vaginal flora were L. crispatus, L. jensenii, and L. inners. L. gasseri and L. plantaris were second most often found species. L. jensenii detection was significantly higher in normal flora group. A. vaginae were mainly detected in patients with bacterial vaginosis. Megasphera and Leptotrichia/Sneathia are more common for patients with pathologic flora. PCR method is the most precise to identify microorganisms in vaginal flora but rather expensive and time consuming than vaginal fluid examination by Nugent score

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Natalija Berza Jana Zodzika Juta Kroica Aigars Reinis Ingus Skadins LindaPiekuse Polina Zalizko Olita Melngaile Rita Pundure Irina Lukojanova OlgaVasina

Keywords

Vaginal microflora, PCR, Lactobacillus, Nugent score

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords