alexa Abstract | Association of Q fever with Autoimmune Hepatitis

Journal of Autoimmune Disorders
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Case Report Open Access

Abstract

Human infection by Coxiella burnetii, a zoonosis, is associated with the development of autoantibodies, though the clinical significance of these is unclear. We describe two patients with high-titer Q fever antibodies associated with autoimmune hepatitis (AIH) as demonstrated on biopsy and supported by autoantibody results. For one, the chronology of serologic results uniquely demonstrates the development of autoantibodies after Q fever antibodies were detected, providing supportive evidence that Coxiella burnetii infection may have been a trigger for autoimmune hepatitis.

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Author(s): Kunatum Prasidthrathsint Michael D Voigt Judy A Streit

Keywords

Coxiella burnetii, Q Fever, Hepatitis, Autoimmune, Type 1 diabetic, Autoimmune, Hepatitis

 
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