alexa Abstract | Biochemical marker as predictor of outcome in perinatal asphyxia.

Current Pediatric Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Birth asphyxia is a leading cause of neonatal mortality in India. At present there is no reliable early marker to predict the outcome in these cases. We conducted this study to evaluate 8-hydroxy 2-deoxyguanosine (8-OHdG) as a biochemical marker for predicting outcome in perinatal asphyxia. Term neonates fulfilling the inclusion criteria were recruited in the study. Cord blood was collected immediately after birth. The concentration of 8-OHdG was analyzed using ELISA. These children were followed up till discharge from hospital with close monitoring for adverse events and morbidities. Neurodevelopmental assessment was done using Baroda developmental screening test up to the age of 6 months. The mean value of 8-OHdG was found to increase with severity of encephalopathy. 8-OHdG values were significantly higher among the cases that expired compared to those who survived. Developmental delay occurred in 29.4% cases. The 8-OHdG levels were significantly higher among the cases who developed developmental delay than those with normal development. It is concluded that, 8-OHdG is a good early serum biochemical marker in predicting the outcome in perinatal asphyxia

To read the full article Peer-reviewed Article PDF image

Author(s): Bahubali D Gane Nandakumar S Vishnu Bhat B Ramachandra Rao Adhisivam B Rojo Joy Prasad P Shruti S


Perinatal asphyxia, Biochemical marker, 8-hydroxy2-deoxyguanosine, Neurodevelopmental outcome

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us