alexa Abstract | Blood carnitine as a biomarker for acute myocardial infarction.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Fatty acid oxidation is the major energy providing pathway of the myocardium and its inhibition impairs myocardial function. Earlier studies have demonstrated the malfunction of heart due to myocardial as well as systemic deficiencies of carnitine which plays an essential role in fatty acids metabolism. This study was aimed to compare the blood levels of carnitine between normal subjects and patients with acute myocardial infarction (AMI). A total of 50 AMI male patients (21 STEMI and 29 NSTEMI) and 144 normal controls were recruited. Blood carnitine was analyzed by liquid chromatography-tandem mass spectrometry. Total carnitine levels were significantly higher in STEMI (57.26 ± 4.51μmol/l) and NSTEMI (54.05 ± 3.52μmol/l) patients as compared to control subjects (35.84 ± 1.15 μmol/l). Similar trends were observed for free carnitine levels. The increased levels of carnitine in the blood stream of AMI patients might have resulted due to the poor uptake and/or increased leakage of carnitine through the ischemic myocardium. The clinical implications of these findings for the risk screening or diagnosis/prognosis of AMI require additional follow-up studies.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Haseeb A Khan Abdullah S Alhomida Syed Shahid Habib Adnan A Khan Mohammad S Ola Nikhat J Siddiqui Samia H Sobki Halima Al Madani


Blood carnitine, acute myocardial infarction, biomarker, diagnosis, prognosis

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us